Lyrically there are some inversions of phrase that go counter to usual speech idioms, which annoys me, but that may just be me. There are also some pretty cynical lines in this one, distrusting "rules," distrusting "pills," distrusting whether anyone knows anything. It's a dangerous soil to plant yourself in. But it's a hard rock song, and for that world it's pretty par for the course.
Musically, gee, there is so much to love. The jaunty pace, the ragtime feel, the inspired Dave Grohl drumming, the scaling chorus guitars that drop into grinding resolutions, the savage middle instrumental with its rousing boil-over of triplets, the Black Sabbath-esque solo/free form that follows.
When the instrumental finally drops out, except for the bass, it's all about the swift drum fill leading the instruments back in. Grohl is a master of creative one-beat pick-up fills. These style points make a song.
Where does heavy music truly live these days? What is its venue in our culture, other than the dive clubs and the occasional festival in the sticks? On a daily basis, this is more brain music than anything now, driving (fast) music at best. $50 reward to the person who finds this music a fitting new habitat. Until then, it'll be bashing around my skull.